And i often wondered about the practice of using the 1st 10Mb of Chr1 as a test alignment target for sequencing runs on the SOLiD machine and how informative that might be.
I wonder since someone probably has some sort of summary statistics of individual chromosomes, is there a particular chromosome that's representative of the whole genome or perhaps a chimera that represents the rest of the chromosomes that one might be good to run through various sequencing platforms to validate results or compare sequencing platform error profiles ...
just a random thought
I've always thought chr20 is the most gentlemanly. 1,6,9 : crazy hetreochromatin. 19 - a zoo of zinc fingers. [1/2]
Stay away from the acrocentrics (13,14,15,21,22), and chr17 has >> duplications. X and Y obviously odd.