1000 Genomes Pilot Paper Published

27 OCTOBER 2010

The 1000 Genomes Project Consortium has published the results of the pilot project analysis in the journal Nature in an article appearing on line today. The paper A map of human genome variation from population-scale sequencing is available from the Nature web site and is distributed under the terms of the Creative Commons Attribution-Non-Commercial-Share Alike licence to ensure wide distribution. Please share our paper appropriately.

Paper:Comparison of Multiple Genome Sequence Alignment Methods

Comparison of Multiple Genome Sequence Alignment Methods
Chen and Tompa, Nature Biotechnology
Xiaoyu Chen and Martin Tompa at the University of Washington in Seattle present their "comparative assessment of methods for aligning multiple genome sequences." In evaluating the level of agreement among the four ENCODE alignments, the team shows that Pecan "produces the most accurate or nearly most accurate alignment in all species and genomic location categories, while still providing coverage comparable to or better than that of the other alignments in the placental mammals."

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing dataHossein Khiabanian, Pieter Van Vlierberghe, Teresa Palomero, Adolfo A Ferrando, Raul RabadanBMC Research Notes 2010, 3:147 (27 May 2010)

Q&A on ChIP-seq

http://www.biomedcentral.com/1741-7007/8/56

Flow scheme of the central steps in the ChIP-seq procedure.

Liu et al. BMC Biology 2010 8:56   doi:10.1186/1741-7007-8-56