SOLiD™ System de novo Accessory Tools 2.0
Usage of pre-assembly error correction: This is an optional tool which was
demonstrated to increase contigs length in de novo assembly by factor of 2 to 3. Do not use this tool if coverage is less than 20x. Overcorrection and under-correction are equally bad for de novo assembly; therefore use balanced number of local and global rounds of error correction. For example, the pipeline will use 1 global and 3 local rounds if reads are 25bp long, and 2 global and 5 local rounds if reads are 50bp long.
Is it just me? I would think it is trivial to implement the correction tool to correct only when the coverage is > 20x. Not sure why you would need human intervention.
