Webinar by Simon Chan, UC Davis on how Pacific Biosciences revealed higher order repeats in centromeres which would have been hidden if you are restricted by the much shorter Sanger reads.
If there was a way to enrich the 'un-sequence-able' portions of the human genome, sequencing by PacBio would perhaps finally yield the COMPLETE human genome.
Would be interesting to see how PacBio fares when Oxford Nanopore Tech has their product out in the wild.
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