Ion Torrent has been improving the Personal Genome Machine's throughput, read length, accuracy, and sample prep and believes it will achieve 400-base reads later this year and be able to sequence a human genome for $1,000 by early 2013, according to the company's founder, Jonathan Rothberg.
At the Consumer Genetics conference in Boston last week, Rothberg said that one of Ion Torrent's customers, the Broad Institute, recently beat the Life Technologies subsidiary's own throughput record for the Ion 316 chip by about 20 percent by generating almost 290 megabases of data in a single run. The 316 chip, which is currently in early-access testing and due to be released at the end of this month, has 6.1 million accessible sensors and is officially supposed to produce only about 100 megabases per run, or a million 100-base reads (IS 3/1/2011).
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