Bioinformatics. 2011 Aug 11. [Epub ahead of print]

ChimeraScan: A tool for identifying chimeric transcription in sequencing data.

Iyer MK, Chinnaiyan AM, Maher CA.

Source

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

Abstract

SUMMARY:

Next Generation Sequencing (NGS) technologies have enabled de novo gene fusion discovery that could reveal candidates with therapeutic significance in cancer. Here we present an open-source software package, ChimeraScan, for the discovery of chimeric transcription between two independent transcripts in high-throughput transcriptome sequencing data.

AVAILABILITY:

http://chimerascan.googlecode.com

CONTACT:

Christopher A. Maher, chrmaher@med.umich.edu

SUPPLEMENTARY INFORMATION:

Available at Bioinformatics online.

PMID:

21840877

[PubMed - as supplied by publisher]