Sunday, 30 May 2010

Paper:Comparison of Multiple Genome Sequence Alignment Methods

Comparison of Multiple Genome Sequence Alignment Methods
Chen and Tompa, Nature Biotechnology
Xiaoyu Chen and Martin Tompa at the University of Washington in Seattle present their "comparative assessment of methods for aligning multiple genome sequences." In evaluating the level of agreement among the four ENCODE alignments, the team shows that Pecan "produces the most accurate or nearly most accurate alignment in all species and genomic location categories, while still providing coverage comparable to or better than that of the other alignments in the placental mammals."

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