Abstract
Due to ongoing advances in sequencing
technologies, billions of nucleotide sequences are now produced on a
daily basis. A
major challenge is to visualize these data for
further downstream analysis. To this end, we present GenomeView, a
stand-alone
genome browser specifically designed to visualize
and manipulate a multitude of genomics data. GenomeView enables users to
dynamically browse high volumes of aligned
short-read data, with dynamic navigation and semantic zooming, from the
whole genome
level to the single nucleotide. At the same time,
the tool enables visualization of whole genome alignments of dozens of
genomes
relative to a reference sequence. GenomeView is
unique in its capability to interactively handle huge data sets
consisting
of tens of aligned genomes, thousands of annotation
features and millions of mapped short reads both as viewer and editor.
GenomeView is freely available as an open source
software package.
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